Sassafras Dosing
Sassafras root bark has been used as an aromatic and carminative at doses of 10 g; however, the carcinogenicity of its constituent safrole has limited its use.
Contraindications
No longer considered safe.
Pregnancy/Lactation
Documented emmenagogue, abortifacient effects. Avoid use.
Sassafras Interactions
None well documented.
Sassafras Adverse Reactions
Besides being a cancer-causing agent, sassafras can induce vomiting, stupor and hallucinations. It can also cause abortion, diaphoresis, and dermatitis.
Toxicology
Sassafras oil and safrole have been banned for use as flavors and food additives by the FDA because of their carcinogenic potential.